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  1. Traditional and complementary medicine (T&CM) is often sought as an significant alternative intervention in stroke prevention and rehabilitation, and is recommended in several guidelines. However, little is kn...

    Authors: Ran-ran Zhu, Jin-xiang Wang, Bei Pan, Hong-hao Lai, Xiao-ting Xu, Long Ge and Lei Fang
    Citation: BMC Complementary Medicine and Therapies 2025 25:184
  2. Authors: Babita Yadav, BCS Rao, Rajiv Narang, Sophia Jameela, Shruti Khanduri, Sakshi Sharma, Drishya Dinesh, Arti Srivastava, Richa Bhardwaj, Bharti Gupta, N Srikanth, Dharamvir Singh Arya and Richa Singhal
    Citation: BMC Complementary Medicine and Therapies 2025 25:183

    The original article was published in BMC Complementary Medicine and Therapies 2025 25:88

  3. Policosanol, a compound generated from sugar cane, consists of alcohols such as octacosanol, hexacosanol, and triacontanol, which possess antioxidant properties. Evaluating the impact of this antioxidant on se...

    Authors: Mohammad Reza Amini, Sara Sadeghi Majd, Marieh Salavatizadeh, Farhang Djafari, Gholamreza Askari and Azita Hekmatdoost
    Citation: BMC Complementary Medicine and Therapies 2025 25:182
  4. Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cholinergic dysfunction, neuroinflammation, oxidative stress, and memory impairment. The Salvia genus has been used since anci...

    Authors: Farid Dabaghian, Mohammad-Reza Delnavazi, Roshanak Hariri, Tahmineh Akbarzadeh, Zahra Tayarani-Najaran, Mohammad Reza Shams Ardekani, Mohammad Sharifzadeh and Mahnaz Khanavi
    Citation: BMC Complementary Medicine and Therapies 2025 25:181
  5. Zingiber cassumunar Roxb., belonging to the Zingiberaceae family, is a medicinal herb commonly found in tropical regions, particularly in Southeast Asia. This research aims to investigate the preventive effects a...

    Authors: Thidaporn Gundom, Wanida Sukketsiri and Pharkphoom Panichayupakaranant
    Citation: BMC Complementary Medicine and Therapies 2025 25:180
  6. The objective of this systematic review was to evaluate existing scientific evidence regarding the effectiveness and safety of preparations of bioactive compounds of the Zingiberaceae family in animal models d...

    Authors: Jonquile T. Williams, Kendra A. Tiani, Margaret J. Foster, Amanda J. MacFarlane, Regan L. Bailey, Patrick J. Stover and Martha S. Field
    Citation: BMC Complementary Medicine and Therapies 2025 25:179
  7. Effective and cost-efficient treatment approaches are crucial in healthcare to optimize patient outcomes. This study evaluates and compares the clinical outcomes and cost-effectiveness of Korean and Western me...

    Authors: Shiva Raj Acharya, Linae Kim and NamKwen Kim
    Citation: BMC Complementary Medicine and Therapies 2025 25:178
  8. Triple-negative breast cancer (TNBC) is a subtype associated with poor prognosis, low survival rates, and high expression of histone deacetylases (HDAC). Treatment with HDAC inhibitors (HDACi) induces the acet...

    Authors: Beate Vajen, Vera Schäffer, Marlies Eilers, Brigitte Schlegelberger and Britta Skawran
    Citation: BMC Complementary Medicine and Therapies 2025 25:177
  9. Authors: Elham Rouhollahi, Soheil Zorofchian Moghadamtousi, Omer Abdalla Ahmed Hamdi, Mehran Fadaeinasab, Maryam Hajrezaie, Khalijah Awang, Chung Yeng Looi, Mahmood Ameen Abdulla and Zahurin Mohamed
    Citation: BMC Complementary Medicine and Therapies 2025 25:176
  10. Immune evasion is a characteristic hallmark of cancer. Immunotherapies aim to activate and support the body's immune system to recognize and fight tumor cells. Induction of immunogenic cell death (ICD) and the...

    Authors: Ulrike Weissenstein, Sibylle Tschumi, Bettina Leonhard and Stephan Baumgartner
    Citation: BMC Complementary Medicine and Therapies 2025 25:175
  11. The registration application of traditional Chinese medicine (TCM) products as new drugs often meets the challenges of lacking clinical evidence from randomized controlled trials (RCT). In recent years, China ...

    Authors: Mingge Xia, Yan Xue, Luwei Zhu, Xianwen Chen, Carolina Oi Lam Ung, Sheng Han, Yunfeng Lai and Hao Hu
    Citation: BMC Complementary Medicine and Therapies 2025 25:174
  12. Parkinson's disease (PD) is a progressive nervous system disorder characterized by dysfunction or degeneration of dopaminergic neurons in the substantia nigra leading to motor symptoms. Parkinson's disease is ...

    Authors: Ngo Binh Thao Nghi, Dao My Linh and Dang Thi Phuong Thao
    Citation: BMC Complementary Medicine and Therapies 2025 25:173
  13. Gynostemma pentaphyllum (Thunb.), a traditional adaptogenic herb, is known for its bioactive components with potential anti-cancer properties. Acute myeloid leukemia (AML) progression is significantly influenced ...

    Authors: Khin Khin Gyi, Songyot Anuchapreeda, Nutjeera Intasai, Montree Tungjai, Siriporn Okonogi, Arihiro Iwasaki, Toyonobu Usuki and Singkome Tima
    Citation: BMC Complementary Medicine and Therapies 2025 25:172
  14. Ninjin’yoeito (NYT), a traditional Japanese Kampo medicine, improves the depression and anxiety in humans and animals, rendering it a novel therapeutic option for post-stroke depression (PSD). Furthermore, phy...

    Authors: Harutoshi Sakakima, Nao Nojima, Akira Tani, Kazuki Nakanishi, Teruki Matsuoka, Ryoma Matsuzaki, Shogo Kakimoto, Yuki Kato, Yuta Tachibe, Masaki Inadome, Takuya Kawatani, Shotaro Otsuka, Keita Mizuno and Ikuro Maruyama
    Citation: BMC Complementary Medicine and Therapies 2025 25:171
  15. Labor pain is a significant challenge during childbirth, highlighting the necessity for effective pain management strategies. Acupressure has been recognized as a non-pharmacological method; however, its effic...

    Authors: Mona Larki, Leila Karimi, Shayesteh Jahanfar, Solmaz Mohammadi and Somayeh Makvandi
    Citation: BMC Complementary Medicine and Therapies 2025 25:170
  16. Depression is a serious mental disorder, and its incidence rate has increased rapidly. Radix Bupleuri (root of Bupleurum chinensis DC. BR)-Radix Paeoniae Alba (root of Paeonia lactiflora Pall. PRA) herb pair has ...

    Authors: Kanglin Cai, Xinyu Chen, Yongkai Cao, Liangdi Ran, Qinpeng Bu, Dajun Hu, Zhitao Feng and Meiqun Cao
    Citation: BMC Complementary Medicine and Therapies 2025 25:168
  17. People experiencing homelessness (PEH) are disproportionately affected by health issues yet remain underserved by the health care system. Emerging findings suggest that complementary medicine (CM) approaches m...

    Authors: Véronique S. Grazioli, Evelyne Hangartner, Patrick Bodenmann, Luana Schaad, Léa Grosjean, Justin Nikles, David J. T. Campbell, Laurent Hyvert, Tshahé Anongba Varela, Susan E. Collins, Caroline Leblanc, Christine Loignon and Chantal Berna
    Citation: BMC Complementary Medicine and Therapies 2025 25:166
  18. Rhinosinusitis is an inflammation of the paranasal sinuses and nasal cavity. It is managed with intra-nasal steroids, nasal saline irrigation, oral antibiotics and/or biologics. Chinese herbal medicines (CHMs)...

    Authors: Jing Cui, Brian H. May, Wenmin Lin, Qiulan Luo, Anthony Lin Zhang, Xinfeng Guo, Chuanjian Lu, Yunying Li and Charlie C. Xue
    Citation: BMC Complementary Medicine and Therapies 2025 25:165
  19. The purpose of this study was to confirm the improvement of peri-implant mucositis (PIM) in patients using the toothpick method (TPM) containing a natural ingredient: Cibotium barometz J. Smith (CB).

    Authors: Yu-Rin Kim and Seoul-Hee Nam
    Citation: BMC Complementary Medicine and Therapies 2025 25:164
  20. Cerebral ischemia–reperfusion injury (CIRI) is a complex pathological process, which can further aggravate the damage of ischemic tissues. Traditional Chinese medicine (TCM) monomers, bioactive compounds extra...

    Authors: Xin Luo, Jing-Yuan Niu and Hui-Sheng Chen
    Citation: BMC Complementary Medicine and Therapies 2025 25:163
  21. Premenstrual syndrome and menstrual symptoms adversely affect approximately 80–95% of women of reproductive age. Aromatherapy interventions are used to reduce premenstrual syndrome and menstrual symptoms. This...

    Authors: Esra Özer, Şerife İrem Döner and Hafize Dağ Tüzmen
    Citation: BMC Complementary Medicine and Therapies 2025 25:162
  22. An updated systematic review of randomized controlled trials (RCTs) was conducted to evaluate the clinical evidence for the use of BVA for musculoskeletal pain. We searched 13 electronic databases up to Decemb...

    Authors: Soo-Hyun Sung, Soobin Jang, Gihyun Lee, Jang-Kyung Park, Sungjoo Lee and Byung-Cheul Shin
    Citation: BMC Complementary Medicine and Therapies 2025 25:161
  23. Rhizosphere bacteria were considered a prospective reservoir of bioactive compounds with significant pharmacological efficacy.

    Authors: Mohamed A. Awad, Shahenda Mahgoub, Hesham S. M. Soliman and Sherif F. Hammad
    Citation: BMC Complementary Medicine and Therapies 2025 25:160
  24. Ya-Kao (YK) is a traditional Thai medicine used to relieve fever and consists of 14 crude drugs. It has been recommended by Thai folk healers and the Department of Thai Traditional and Alternative Medicine for...

    Authors: Naruemon Perstwong, Asma Binalee, Khwanlada Kobtrakul, Wongsakorn Phongsopitanun, Kittipong Sanookpan, Sudartip Areecheewakul, Visarut Buranasudja and Sornkanok Vimolmangkang
    Citation: BMC Complementary Medicine and Therapies 2025 25:159
  25. Although the Enhanced Recovery After Surgery (ERAS) protocol has been optimised, postoperative gastrointestinal dysfunction (POGD) still significantly hampers recovery after laparoscopic nephrectomy, thus addi...

    Authors: Yang Zhenjie and Zhang Xiang
    Citation: BMC Complementary Medicine and Therapies 2025 25:158
  26. Postpartum depression and anxiety are common problems in primiparous women, which can negatively affect Maternal-infant bonding and lead to sexual disorders. It’s important to prevent and treat these issues, e...

    Authors: Elham Pishevar Hamlbar, Mojgan Mirghafourvand, Elnaz Shaseb and Mahin Kamalifard
    Citation: BMC Complementary Medicine and Therapies 2025 25:157
  27. Cancer cases have been on the rise globally and several treatment strategies have been developed but mortality rates remain high. Zimbabwe, like many other countries, has also experienced a surge in cancer cas...

    Authors: Sigcono Mlilo, Samson Sibanda, Simbarashe Sithole, Stanley Mukanganyama and Yogehkumar S. Naik
    Citation: BMC Complementary Medicine and Therapies 2025 25:156
  28. Corticosterone stimulation has profound physiological and neurological effects on individuals, necessitating effective interventions to mitigate its impact. Current therapeutic approaches for corticosterone st...

    Authors: Xuedi Kang, Ting Wang, Haiping Wan, Wenjun Fu and Songjun Lin
    Citation: BMC Complementary Medicine and Therapies 2025 25:155
  29. Non-alcoholic steatohepatitis-associated hepatocellular carcinoma (NASH-HCC) accounts for an increasing proportion of HCC cases. Currently, effective pharmacological options for treating both NASH and NASH-HCC...

    Authors: Qiurui Li, Meng Wang, Xuekuan Huang, Shang Wang, Chunli Li, Pan Li, Wei Xiang, Ling Yao, Chengdan Deng, Mingming Zhang and Jianwei Wang
    Citation: BMC Complementary Medicine and Therapies 2025 25:154
  30. Myelophil is a standardized ethanol extract of Astragali Radix and Salviae Miltiorrhizae Radix, which has been developed based on clinical experience in traditional Korean medicine practices for patients with une...

    Authors: Ji-Yun Kang, Dong-cheol Baek, Jin-Seok Lee and Chang-Gue Son
    Citation: BMC Complementary Medicine and Therapies 2025 25:153
  31. This study aims to evaluate the efficacy of baicalein, a flavonoid derived from Scutellaria baicalensis, against Staphylococcus aureus (S. aureus), focusing on its inhibitory and eradicative effects on biofilms, ...

    Authors: Aerman Alimu, Xiaoyu Wu, Dongwei Huang, Chenghan Chu, Baiqi Pan, Yang Xing, Weishen Chen, Lingli Long and Puyi Sheng
    Citation: BMC Complementary Medicine and Therapies 2025 25:152
  32. Insulin secretion deficiency and increased insulin resistance are key pathological pathways that lead to pre-diabetes. Without intervention, pre-diabetes can easily develop into type 2 diabetes mellitus. Howev...

    Authors: Jialuo Cai, Yilin Zhu, Guiming Deng, Linqi Ouyang, Wangzhong Xiao, Fang Zhou, Yuanshan Han, Feiyun Yuan, Li Huang and Xiaoping Li
    Citation: BMC Complementary Medicine and Therapies 2025 25:151
  33. Chinese patent medicines, produced using advanced pharmaceutical techniques and available in various forms, including powders, granules, tablets, pills, and capsules, finds extensive utilization among Western ...

    Authors: Qing Zhao, Lin Lin, Ada Kwan, Huanyu Hu, Lei Wu, Yuanbin Chen, Zengping Shi, Bohan Li, Jingmin Xiao, Guangyu Tong, Wenjun He, Huanyuan Luo, Qingqing Li, Run Wang, Dongmei Zhong, Siyuan Liu…
    Citation: BMC Complementary Medicine and Therapies 2025 25:150
  34. The increasingly rising incidence of cancer among children and adolescents has led to notable psychological challenges for this population. Art therapy, classified within the realm of complementary and alterna...

    Authors: Shishuang Zhou, Huiyuan Li, Yuan Yang, YiShu Qi, Weiwei Liu, Lin Mo and Cho Lee Wong
    Citation: BMC Complementary Medicine and Therapies 2025 25:149
  35. The presented study aimed to assess the efficacy of crude leaf hydroethanolic extracts from blackcurrant, fig, and grape leaves in reversing antibiotic resistance and enhancing chemotherapeutic efficacy. The v...

    Authors: Mikayel Ginovyan, Silvard Tadevosyan, Anahit Shirvanyan, Anush Babayan, Barbara Kusznierewicz, Izabela Koss-Mikołajczyk, Marika Mróz, Agnieszka Bartoszek and Naira Sahakyan
    Citation: BMC Complementary Medicine and Therapies 2025 25:148
  36. Berberine is an isoquinoline alkaloid isolated from Chinese herb coptis chinensis and other berberis plants which can be used to treat a wide range of chronic diseases. However, the current research evidence o...

    Authors: Lanjun Shi, Wenya Wang, Chengyang Jing, Jing Hu and Xing Liao
    Citation: BMC Complementary Medicine and Therapies 2025 25:147
  37. Fecal microbiota transplantation (FMT) seems to be a promising approach in ulcerative colitis (UC) management with the aim of repopulating a patient’s dysbiotic microbiota with beneficial bacteria and restore ...

    Authors: Anna Kamlárová, Monika Kvaková, Ľuboš Ambro, René Link, Izabela Bertková, Zdenka Hertelyová, Martin Janíčko, Emília Hijová and Jana Štofilová
    Citation: BMC Complementary Medicine and Therapies 2025 25:145
  38. Myrtaceae and Podocarpaceae botanical families include several aromatic species that have been proven to have diverse pharmacological potential, especially antimicrobial effects. Additionally, plants of both f...

    Authors: Heba A. M. Ezzat, Nermin A. Younis, Mai M. Zafer, Amel M. Kamal, Mohamed I. S. Abdelhady and Mohamed S. Mady
    Citation: BMC Complementary Medicine and Therapies 2025 25:144
  39. Rhizomes of Curcuma wanenlueanga Saensouk, Thomudtha & Boonma have been used in Thai traditional medicine and are included as an ingredient in a Thai traditional liniment formula listed by the Ministry of Public ...

    Authors: Wisuwat Thongphichai, Hasriadi Hasriadi, Peththa Wadu Dasuni Wasana, Sanith Sri Jayashan, Boonchoo Sritularak, Pasarapa Towiwat and Suchada Sukrong
    Citation: BMC Complementary Medicine and Therapies 2025 25:143
  40. Hezi Qingyou Formula (HZQYF) is a clinical formulation known for its efficacy in treating gastrointestinal diseases. Nevertheless, its specific impact and underlying mechanism of action in gastric cancer remai...

    Authors: Zhong Feng, Ling Ou, Hui Li, Yajie Hao, Ruixia Wei, Guimin Zhang and Meicun Yao
    Citation: BMC Complementary Medicine and Therapies 2025 25:142
  41. Qigong and Tai Chi (QTC) have been adopted by cancer patients as the complementary treatment to their conventional care. This umbrella review aimed to evaluate the clinical effectiveness of QTC in cancer patie...

    Authors: Jing Xu, Hong Li, Daniel Man-yuen Sze, Vincent Wan Shing Chan and Angela Wei Hong Yang
    Citation: BMC Complementary Medicine and Therapies 2025 25:141
  42. Diabetes Mellitus is often a long-term health condition that continues to raise concerns regarding the burden upon an individual’s mental health, due to the commitment required for day-to-day self-care. People...

    Authors: Tracey Oorschot, Jon Adams and David Sibbritt
    Citation: BMC Complementary Medicine and Therapies 2025 25:140
  43. Chronic obstructive pulmonary disease (COPD) and heart failure (HF) pose significant challenges to patients and the health systems that care for them. Music therapy has the potential to address these challenge...

    Authors: Haitong Yu, Angelique Foss, Tracy L. Segall, Seneca Block, Kayleigh Risser, Rab Razzak, Michael Zacharias, Catalina V. Teba and Samuel N. Rodgers-Melnick
    Citation: BMC Complementary Medicine and Therapies 2025 25:139
  44. Aging is a physiological process that impacts multiple systems of organs. Alzheimer’s disease (AD) is the most common form of dementia in the elderly, and it is a major problem in aging societies. The developm...

    Authors: Kaikwa Wuttisa, Pol Sookpotarom, Benjamaporn Poopan, Chantanapa Chantarangkul, Praewpannarai Jamjuree, Jirapat Namkeaw, Thiranut Jaroonwitchawan and Malai Taweechotipatr
    Citation: BMC Complementary Medicine and Therapies 2025 25:137
  45. One of the Iranian medicinal plants is Alhagi maurorum, which belongs to the Fabaceae family. The plant is used to treat different conditions, such as aphthous ulcers, cardiac pains, hemorrhoids, kidney stones, d...

    Authors: Fatemeh Hoseinpour, Mohammad Hashemnia, Hadi Cheraghi, Mohammad Mohsen Salari Asl, Farshad Zare and Iman Ahmadi Zanjani
    Citation: BMC Complementary Medicine and Therapies 2025 25:136
  46. Chronic stress is a risk factor for the development of colorectal cancer (CRC). Xiao-chai-hu-tang (XCHT) is a traditional Chinese medicine prescription and has been widely used to treat chronic stress-related ...

    Authors: Wang Yao, Dong-Ming Hua, Ying-Ru Zhang, Yi-Yang Zhao, Ying Feng, Zhao-Zhou Zhang, Zhong-Ya Ni, Hai-dong Guo, Yun-Feng Guan and Yan Wang
    Citation: BMC Complementary Medicine and Therapies 2025 25:135
  47. It is widely believed that Silybum marianum (Silymarin) alleviates liver injury arising from various etiologies with different degrees of damage through its anti-inflammatory and antioxidant activities. This meta...

    Authors: Kasra Shahsavari, Shireen Shams Ardekani, Mohammad Reza Shams Ardekani, Majid Mokaber Esfahani, Hossein Kazemizadeh, Tannaz Jamialahmadi, Mehrdad Iranshahi, Mahnaz Khanavi and Maede Hasanpour
    Citation: BMC Complementary Medicine and Therapies 2025 25:134