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  1. This research assessed the potential role of okra (Abelmoschus esculentus L.) extract on periodontal tissue wound healing by evaluating its effects on human periodontal ligament fibroblast (hPDLF), human gingival...

    Authors: Umut Ulaş Tosun, Sema Tuğçe Aydın, Ayşegül Tiryaki, Dilruba Baykara, Aleyna Yakut, Erkan Rayaman, Turgut Taşkın, Canan Ekinci Doğan, Oğuzhan Gündüz and Ömer Birkan Ağralı
    Citation: BMC Complementary Medicine and Therapies 2025 25:84
    Content type: Research Published on:

  2. The natural compound cedrol possess anti-inflammatory and antioxidant properties. We sought to assess the neuroprotective effect of cedrol in an animal model of transient global ischemia/reperfusion (I/R) injury.

    Authors: Samira Asgharzade, Amir Mahmoud Ahmadzadeh, Ali Mohammad Pourbagher-Shahri and Fatemeh Forouzanfar
    Citation: BMC Complementary Medicine and Therapies 2025 25:83
    Content type: Research Published on:

  3. Zataria multiflora (Z. multiflora), also known as Shirazi thyme, is recognized for its medicinal properties, including antioxidant, anti-inflammatory, and immunomodulatory effects. Its longstanding use in traditi...

    Authors: Naheed Aryaeian, Fahimeh Agh, Ali Nouri, Seyed Mojtaba Ghoreishy, Amirhossein Ramezani Ahmadi, Narges Dehghanseresht, Narges Sadeghi and Mehrnaz Morvaridi
    Citation: BMC Complementary Medicine and Therapies 2025 25:82
    Content type: Research Published on:

  4. Emerging evidence has shown that mindfulness-based cognitive therapy (MBCT) is effective in improving depressive symptoms in the older population. However, the accessibility to MBCT is limited by the shortage ...

    Authors: Yun-Han Wang, Yun-Lin Wang, Dara Kiu Yi Leung, Zuna Loong Yee Ng, Oscar Long Hung Chan, Stephanie Ming Yin Wong, Raymond Chi Leung Chan, Tianyin Liu, Gloria Hoi Yan Wong and Terry Yat Sang Lum
    Citation: BMC Complementary Medicine and Therapies 2025 25:81
    Content type: Research Published on:

  6. Researchers have searched for plant-derived medicines over the last few decades. Although much of the focus has been on medicinal herbs, many vegetables, such as sweetpotato, have also been discovered to have ...

    Authors: Sochinwechi Nwosisi, Dilip Nandwani and Elbert Lewis Myles
    Citation: BMC Complementary Medicine and Therapies 2025 25:79
    Content type: Research Published on:

  7. Emergence of multidrug resistant pathogens has opened new vistas for novel drug discovery or combinatorial drug surveillance, often in form of some natural products, which is considered to be cheap and safe. I...

    Authors: Lipsa Panigrahy, Swarna Rani Panda, Shaikh Ameeruddin, N. Susmita Pradhan and Sarita Das
    Citation: BMC Complementary Medicine and Therapies 2025 25:78
    Content type: Research Published on:

  8. Sadness can be a harbinger of serious medical conditions and a primary manifestation of depressive symptoms. Music is a promising modality for regulating sadness, although its effect on participants, whether w...

    Authors: Xuanyi Wang, Tian Lu, Bian Zhou, Wanlin Chen, Jing Zheng, Hang Chen and Shulin Chen
    Citation: BMC Complementary Medicine and Therapies 2025 25:77
    Content type: Research Published on:

  9. Food medicine homology originated in ancient China and has been officially named food-medicine dual-purpose substances (FMS). However, the relationship between residents’ knowledge, attitudes, practices (KAP) ...

    Authors: Haixian Jia, Chunyu Li, Zheng Li, Yao Zhao, Zhonghui Chen, Jiali Duan and Xiaochen Ma
    Citation: BMC Complementary Medicine and Therapies 2025 25:76
    Content type: Research Published on:

  10. Danggui-Shaoyao-San (DSS) is a classic Chinese medicine formula that has been extensively studied for its efficacy in treating Alzheimer’s disease (AD). However, its mechanism of action is still unclear.

    Authors: Yi Huang, Yingying Zhai, Di Zhao, Mingan Wu, Qi Shen, Wei Zhao, Qi Wang, Limei Yao and Weirong Li
    Citation: BMC Complementary Medicine and Therapies 2025 25:75
    Content type: Research Published on:

  11. Each year, over 20,000 men are diagnosed with cancer in Norway, and approximately 150,000 men who have previously been diagnosed with cancer are currently alive. Many of these cancer survivors encounter a rang...

    Authors: Agnete E. Kristoffersen, Kiwumulo Nakandi, Arne Johan Norheim, Mona Bjelland, Jorunn V. Nilsen and Eran Ben-Arye
    Citation: BMC Complementary Medicine and Therapies 2025 25:74
    Content type: Research Published on:

  12. Malaria is an infectious disease, which has continued to cause inconceivable loss of lives every year, almost unabatedly. Currently, it has become more difficult to treat the disease due to the emergence and s...

    Authors: Ikponmwosa Owen Evbuomwan, Oluyomi Stephen Adeyemi and Olarewaju Michael Oluba
    Citation: BMC Complementary Medicine and Therapies 2025 25:73
    Content type: Research Published on:

  13. The purpose of this study is to evaluate the effectiveness of music therapy on physiological response and anxiety in perioperative ophthalmic patients. Furthermore, to explore the differentiation of interventi...

    Authors: Jingyu Yan, Jun Liu, Jingpin Wang, Wei Chen and Jinping Hu
    Citation: BMC Complementary Medicine and Therapies 2025 25:72
    Content type: Systematic Review Published on:

  14. Supplementation with pine bark extract (PBE) may improve risk factors associated with cardiometabolic syndrome (CMS). The effects of PBE supplementation on cardiometabolic risk factors were evaluated in this s...

    Authors: Shooka Mohammadi, Tamas Fulop, Abdelouahed Khalil, Sara Ebrahimi, Motahareh Hasani, Somayeh Ziaei, Farnaz Farsi, Elham Mirtaheri, Mostafa Afsharianfar and Javad Heshmati
    Citation: BMC Complementary Medicine and Therapies 2025 25:71
    Content type: Systematic Review Published on:

  15. Clinical studies have shown that Compound Kushen Injection (CKI) can alleviate the inflammatory symptoms of radiation enteritis. However, the mechanism of action remains unclear. The aim of this study was to e...

    Authors: Wenjing Xu, Liping Gao, Wenjuan Zou, Xiaohui Tang, Weiqi Nian, Weiqin Zheng, Rongzhong Huang and Pei Wang
    Citation: BMC Complementary Medicine and Therapies 2025 25:70
    Content type: Research Published on:

  16. Auriculotherapy has become a promising complementary therapy and is widely used to manage various symptoms and diseases. However, little is known about patients’ knowledge and attitudes. This study aimed to id...

    Authors: Ying Zhang, Kun Li, Siyuan Wu, Keping Zhu, Fuchao Xie, Binbin Zhu, Lijun Wang and Wei Wang
    Citation: BMC Complementary Medicine and Therapies 2025 25:69
    Content type: Research Published on:

  18. Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder with significant metabolic and hormonal dysregulation. Marjoram (Origanum majorana L.), known for its medicinal properties, has potential in managin...

    Authors: Aliaa M. Elfiky, Reham S. Ibrahim, Amira R. Khattab, Mai O. Kadry, Naglaa M. Ammar and Eman Shawky
    Citation: BMC Complementary Medicine and Therapies 2025 25:67
    Content type: Research Published on:

  19. To explore the potential mechanism of the treatment of lung cancer (LC) with Codonopsis Radix.-Hedysarum Multijugum Maxim.-Atractylodes Macrocephala Koidz. (CHA).

    Authors: Bin He, Jun Cui, Zengwang Zhang and Yongjun Zhang
    Citation: BMC Complementary Medicine and Therapies 2025 25:66
    Content type: Research Published on:

  20. Ovarian cancer is one of most common gynaecologic malignancy and ranks third in cancer-related deaths among women. Ursolic acid (UA) is a pharmacologically active pentacyclic triterpenoid isolated from a large...

    Authors: Ru Zhang, Zhaopeng Zhang, Lulu Xie, Ziqing Yu, Rui Gao, Zhi-Run Zhang, Ying Zhang, Xuyang Wei, Yang Chen, Sue Jiao, Yiren Gao and Jun-Peng Guo
    Citation: BMC Complementary Medicine and Therapies 2025 25:65
    Content type: Research Published on:

  21. There is limited information on complementary medicine (CM) use among older adults living in residential aged care facilities (RACFs). This study aimed to determine the prevalence and predictors of CM use and ...

    Authors: Narjis Batool, Magdalena Z. Raban, Karla L. Seaman, Johanna I. Westbrook and Nasir Wabe
    Citation: BMC Complementary Medicine and Therapies 2025 25:64
    Content type: Research Published on:

  22. Respiratory dysfunction is a common nonmotor symptom in patients with Parkinson’s disease that may be easily overlooked. Incorporating respiratory function rehabilitation into routine rehabilitation programs f...

    Authors: Huimei Yin, Oumei Cheng, Xu Zhang, Fengying Quan, Yujiao Zhang, Hongzhou Zuo, Jianrong Zhou and Shi-Qi Xie
    Citation: BMC Complementary Medicine and Therapies 2025 25:63
    Content type: Research Published on:

  23. Multidrug-resistant (MDR) bacteria pose a significant threat to human health worldwide by increasing the harmful impact of traditional synthetic antibiotics. Traditional medicinal plants have bioactive metabol...

    Authors: Hend Khairy Fekry Ghaly, Fatema Aly Al-Yamany Younis, Azza Mahmoud Soliman and Sabha Mahmoud El-Sabbagh
    Citation: BMC Complementary Medicine and Therapies 2025 25:62
    Content type: Research Published on:

  24. Dendrobium amoenum is known for its aesthetic and medicinal values but it is threatened due to loss of wild resources. Plant tissue culture promotes wild resource protection and paves the way for secondary metabo...

    Authors: Mukti Ram Paudel, Sujata Sharma, Pusp Raj Joshi, Basant Pant, Sven H. Wagner, Pritam Gurung, Krishna Kumar Pant and Bijaya Pant
    Citation: BMC Complementary Medicine and Therapies 2025 25:61
    Content type: Research Published on:

  25. Authors: Esmaeil Karami, Zahra Goodarzi, Seyed Jamaleddin Shahtaheri, Mehrafarin Kiani, Mohammad Faridan and Mahmoud Ghazi-Khansari
    Citation: BMC Complementary Medicine and Therapies 2025 25:60
    Content type: Editorial Expression of Concern Published on:

  26. Cervical cancer remains a significant public health concern, especially for low-and middle-income countries. This study explores the dual potential of medicinal plant extracts as both anticancer agents and imm...

    Authors: Harsha Vaghasia, Rahul Patel, Jignesh Prajapati, Krupa Shah, Meenu Saraf and Rakesh M Rawal
    Citation: BMC Complementary Medicine and Therapies 2025 25:59
    Content type: Research Published on:

  27. Breast cancer is chemo-resistant and highly metastatic, often resulting in patient mortality. One of the primary factors contributing to the metastasis and chemotherapy resistance is the presence of cancer ste...

    Authors: Nehal M. EL-Deeb, Omar M. Ibrahim, Ayman M. Kamel, Ahmed I. Gomaa and Ahmed M. Kenawy
    Citation: BMC Complementary Medicine and Therapies 2025 25:58
    Content type: Research Published on:

  28. Chronic fatigue syndrome (CFS) is a chronic disease characterized by fatigue, complex symptoms and long duration. It incurs significant economic costs every year. Qigong Tuina therapy (QTT), a traditional Chin...

    Authors: Haotian Han, Guanghui An, Jiahe Cui, Fangfang Xie, Hongyu Yue, Chaoqun Xie, Jianwen Ma, Guangdong Wang and Fei Yao
    Citation: BMC Complementary Medicine and Therapies 2025 25:57
    Content type: Study Protocol Published on:

  29. To evaluate the effect at 3 months of an intensive cervical traction protocol on disability in people with cervical radiculopathy and compare with placebo traction.

    Authors: Grégoire Cormier, Chloé Moreau, Emilie Scalisi, Lydie Pastor and Thomas Rulleau
    Citation: BMC Complementary Medicine and Therapies 2025 25:56
    Content type: Study Protocol Published on:

  30. Wounds in both humans and canines are injuries that result in damage to the body's tissues. Wounds can range from minor superficial scratches to severe and deep injuries. Complications of wounds, both in human...

    Authors: Morgan Detering, Ashley Langland, Anabel Terry and Jeffrey Langland
    Citation: BMC Complementary Medicine and Therapies 2025 25:55
    Content type: Research Published on:

  31. Asthma is a chronic disease characterized by airway inflammation and obstruction. Treatment aims to control symptoms with minimal medication, using disease-controlling and symptom-relieving drugs. Inhaled ster...

    Authors: Sung-Woo Kang, Hae-Seong Nam, Yang-Chun Park, Jun-Yong Choi, Ki-Tae Kim, Seo-Jung Ha, Kwan-Il Kim, Hee-Jae Jung and Beom-Joon Lee
    Citation: BMC Complementary Medicine and Therapies 2025 25:54
    Content type: Study Protocol Published on:

  32. The World Health Organization encourages governments to develop legal frameworks for the regulation of traditional medicines to ensure safety, quality, and efficacy. There is inadequate published research on t...

    Authors: J.S. Mponda, A.S. Muula, A. Choko, A. J. Ajuwon and J. O. Moody
    Citation: BMC Complementary Medicine and Therapies 2025 25:53
    Content type: Research Published on:

  33. The treatment of severe bleeding, stopping pregnancies, and other gynecologic conditions have all been addressed by women using traditional medicines and methods. Even though research has been done to explore ...

    Authors: Alemnew Wale, Aychew Kassie, Nahom Solomon and Desalegn Girma
    Citation: BMC Complementary Medicine and Therapies 2025 25:52
    Content type: Research Published on:

  34. The human microbiome plays a vital role in human health, mediated by the gut–brain axis, with a large diversity of functions and physiological benefits. The dynamics and mechanisms of meditations on oral and g...

    Authors: Sanjay Swarup, Abhishek Gupta, Marianne Chung, Vaishnavi Radhakrishnan, Valerie Davis, Michael D. J. Lynch, Trevor C. Charles, Jiujun Cheng and Glenn Mendoza
    Citation: BMC Complementary Medicine and Therapies 2025 25:51
    Content type: Research Published on:

  35. Pulsed electromagnetic fields (PEMFs) therapy was extensively investigated to treat wound healing, which is a highly metabolically demanding process. However, the effect of PEMFs on energy metabolism in wound ...

    Authors: Feng Liao, Yamei Li, Zhou Zhang, Qian Yu and Huifang Liu
    Citation: BMC Complementary Medicine and Therapies 2025 25:50
    Content type: Research Published on:

  36. This study focuses on the investigation of the antioxidant and anti-inflammatory activities of alcohol extracts from Ribes nigrum leaves on murine BV-2 microglial Wt and Acyl-CoA oxidase 1 deficient (Acox1−/−) ce...

    Authors: Alvard Minasyan, Vivien Pires, Catherine Gondcaille, Mikayel Ginovyan, Marika Mróz, Stéphane Savary, Mustapha Cherkaoui-Malki, Barbara Kusznierewicz, Agnieszka Bartoszek, Pierre Andreoletti and Naira Sahakyan
    Citation: BMC Complementary Medicine and Therapies 2025 25:49
    Content type: Research Published on:

  37. Astragaloside IV (AS-IV) is a bioactive saponin extracted from Radix Astragali, and it is reported to promote osteoblast differentiation while inhibiting osteoclastogenesis. However, the mechanism of AS-IV in ...

    Authors: Chun Guo, Yangyang Li, Ruijuan Yang, Mingzhang Xie, Xiangfeng Chen, Zhiqun Che, Zhixia Wang, Bin Zhong, Yanhong Luo and Xiao-Min Leng
    Citation: BMC Complementary Medicine and Therapies 2025 25:48
    Content type: Research Published on:

  38. Since ancient times, plants with medicinal properties have played a crucial role in the prevention and treatment of various diseases. The current study focuses on the formulation and assessment of Vitis vinifera ...

    Authors: Ahmad M. Eid, Haneen Al-Hawari, Shahd Nazzal and Samera Khudarieh
    Citation: BMC Complementary Medicine and Therapies 2025 25:47
    Content type: Research Published on:

  39. Premature ovarian insufficiency (POI), a condition impacting women under 40, is rising globally, posing significant risks to fertility, bone health, and cardiovascular function. Conventional hormone replacemen...

    Authors: Yin Peng, Jian Liu, Yang Li, Guangning Nie, Fangping Cheng, Daning Feng, Qiaolin Du, Jian Huang and Hongyan Yang
    Citation: BMC Complementary Medicine and Therapies 2025 25:46
    Content type: Study Protocol Published on:

  40. The present study aimed to perform phytochemical investigation of various fractions of the aerial parts of Senecio laetus Edgew for its bio-constitution and to pharmacologically evaluate these fractions for antio...

    Authors: Rukhsar Wadoo, Tabasum Ali, Ifat Jan, Suhail Ahmad Mir, Asif Amin, Raies Qadri, Sultan Alshehri, Faiyaz Shakeel, Ghulam Nabi Bader and Shahid Ud Din Wani
    Citation: BMC Complementary Medicine and Therapies 2025 25:45
    Content type: Research Published on:

  41. Stroke is a leading cause of morbidity and mortality globally, with Nigeria having one of the highest stroke mortality rates in Africa. The burden of stroke is particularly high in middle-aged individuals, who...

    Authors: Uchenna Prosper Okonkwo, Chidera Chibuikem Fortunate, Sochima Johnmark Obiekwe, Uchechukwu Martha Chukwuemeka, Christiana Nkiru Okafor, Augustine Asiduba Igwe and Jovita Ada Daniel
    Citation: BMC Complementary Medicine and Therapies 2025 25:44
    Content type: Research Published on:

  42. Honey has been successfully used in wound care and cosmetics because of its effective biological properties, including antibacterial, antioxidant, and anti-inflammatory activities. Polyphenols, particularly ph...

    Authors: Anna Nowak, Anna Muzykiewicz-Szymańska, Magdalena Perużyńska, Edyta Kucharska, Łukasz Kucharski, Karolina Jakubczyk, Paulina Niedźwiedzka-Rystwej, Justyna Stefanowicz-Hajduk, Marek Droździk and Juraj Majtan
    Citation: BMC Complementary Medicine and Therapies 2025 25:43
    Content type: Research Published on:

  43. Massage is suggested to be an effective treatment for chronic plantar heel pain (PHP). There is, however, no scientific evidence to support this claim. In the present study Traditional Thai Massage (TTM) has b...

    Authors: Supamas Somphai, Wiraphong Sucharit, Punnee Peungsuwan, Neil Roberts and Uraiwan Chatchawan
    Citation: BMC Complementary Medicine and Therapies 2025 25:42
    Content type: Research Published on:

  44. With the growing ubiquity of electronic devices, the incidence of upper crossed syndrome (UCS) is increasing every year and tends to affect younger populations. The study was designed to assess the effect of c...

    Authors: Yue Guo, Ming Li, Chaowei Xie, Xiaoyan Liu, Yushan Chen, Jun Yang, Yuxue Wu, Shaoqing Chen, Shizhong Wang and Jianping Lin
    Citation: BMC Complementary Medicine and Therapies 2025 25:41
    Content type: Research Published on:

  45. Tangeretin, a flavone compound (O-polymethoxylated) naturally present in tangerine and other citrus peels has demonstrated effectiveness as an anti-inflammatory and neuroprotective agent in several disease mod...

    Authors: Olalekan Bukunmi Ogunro, Mojisola Esther Karigidi, Gideon Ampoma Gyebi, Areej Turkistani and Ahmad H. Almehmadi
    Citation: BMC Complementary Medicine and Therapies 2025 25:40
    Content type: Research Published on:

  46. Pseudomonas aeruginosa is a prominent multidrug-resistant and biofilm-forming bacteria. Mono-floral honey, enriched with a variety of biological compounds, can be categorized as medical-grade honey due to its not...

    Authors: Mustafa Riyadh Alshaybawee, Shahrzad Asgari, Paria Ghadersoltani, Ahmadreza Mehrabian and Parastoo Saniee
    Citation: BMC Complementary Medicine and Therapies 2025 25:39
    Content type: Research Published on:

  47. Drug rehabilitation is a challenging process that impacts both the physical and mental health of individuals. Traditional martial arts, such as Health Qigong, and closed motor exercises, such as power cycling,...

    Authors: Guang Yang, Deyu Meng, Shichun He, Meiqi Wei, Man Li, Lu Zhang, Zhendong Pan and Ziheng Wang
    Citation: BMC Complementary Medicine and Therapies 2025 25:38
    Content type: Research Published on:

  48. Post-Acute COVID Syndrome (PACS) is a complex disorder that currently lacks effective evidenced-based therapies to manage it. This randomized controlled trial aims to evaluate the effects of balneotherapy (BT)...

    Authors: Diana Ovejero, Anna Ribes, Judit Villar-García, Marta Trenchs-Rodriguez, Daniel Lopez, Xavier Nogués, Robert Güerri-Fernandez and Natalia Garcia-Giralt
    Citation: BMC Complementary Medicine and Therapies 2025 25:37
    Content type: Research Published on:

  49. Cotinus coggygria has a long history of use in traditional medicine in Europe and Asia. The aim of study was to explore the cytotoxicity of extracts (EE-ethanol, MME-methylene chloride/methanol, and WE-water) and...

    Authors: Ivana Pašić, Miroslav Novaković, Vele Tešević, Slobodan Milosavljević, Nina Petrović, Tatjana Stanojković and Ivana Z. Matić
    Citation: BMC Complementary Medicine and Therapies 2025 25:36
    Content type: Research Published on:

  50. Syzygium guineense (Wild.) DC. is a wild indigenous tree widely used as a traditional medicine for various human ailments in Ethiopia. The purpose of this study was to quantify total phenolic (TPC) and total flav...

    Authors: Engeda Dessalegn, Mengisteab Mathewos, Hiwot Gebremeskel and Nigatu Tuasha
    Citation: BMC Complementary Medicine and Therapies 2025 25:35
    Content type: Research Published on:
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ISSN: 2662-7671

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