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Table 1 Risk of bias for randomized controlled trials, assessed according to the Revised Cochrane risk-of-bias tool for randomized trials (RoB 1)

From: The effects of policosanol supplementation on creatinine: a systematic review and dose–response meta-analysis of randomized controlled trials

Publications

Random sequence generation

Allocation concealment

Selective reporting

Blinding (participants and personnel)

Blinding (outcome assessment)

Incomplete outcome data

other source of bias

1. Aneiros (1993) [41]

L

U

L

L

H

L

L

2. Aneiros (1995) [22]

L

U

L

L

H

L

L

3. Arteche-Hidalgo (2020) [42]

L

U

L

L

H

L

L

4. Castano (1) (1995) [43]

L

U

L

L

H

L

L

5. Castano (1996) [44]

L

U

L

L

H

L

L

6. Castano (1) (2001) [45]

L

U

L

L

H

L

L

7. Castano (2002) [46]

L

U

L

L

H

L

L

8. Castano (2003) [47]

L

U

L

L

H

L

L

9. Castano (2005) [48]

L

U

L

L

H

L

L

10. Castano (2006) [49]

L

U

L

L

H

L

L

11. Castano (2) (1995) [50]

L

U

L

L

H

L

L

12. Castano (1997) [29]

L

U

L

L

H

L

L

13. Castano (2007) [51]

L

U

L

L

H

L

L

14. Castano (2) (2001) [52]

L

U

L

L

H

L

L

15. Marcello (2000) [53]

L

U

L

L

H

L

L

16. Más (1999) [23]

L

U

L

L

H

L

L

17. Pons (1992) [50]

L

U

L

L

H

L

L

18. Pons (1994) [44]

L

U

L

L

H

L

L

19. Swanson (2011) [54]

L

U

L

L

H

L

L

20. Wang (2018) [55]

L

U

L

L

H

L

L

21. Zardoya (1996) [56]

L

U

L

L

H

L

L

22. Cho (2023) [57]

L

U

L

L

H

L

L

  1. L Low risk of bias, H High risk of bias, U Unknown