Fig. 8

Levels of p53, pro-caspase3 and cleaved-caspase3 protein following 48 h of exposure to IC10, IC15, and IC20 concentrations of F-EtOAc and F10 in (A and B) EoL-1 cells and (C and D) MV4-11 cells. GAPDH was used as a loading control. Histograms show the mean ± SD of three independent experiments. Doxorubicin was used as positive control (PC) in this experiment. The asterisk (*) indicates significant difference compared to vehicle control (VC); (*p < 0.05, **p < 0.001, one-way ANOVA)