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Table 5 Frequently used ingredients in oral herbal formulae in classical citations by inclusion in clinical trials and modern Chinese pharmacopoeia

From: Chinese herbal medicines for rhinosinusitis: a text-mining study with comparisons to contemporary research and clinical guidance

Scientific name (main species)a

Herb name

Frequency (rank) in classical citations [year range]b

Frequency (rank) in formulae in SR 1c

Frequency (rank) in formulae in SR 2c

Used for RS in modern Chinese pharmacopoeia (Y/N)

Magnolia spp. flower bud

Xin yi (hua)

162 (1) [1117–1949]

30 (1)

15 (1)

Yesd

Angelica dahurica (Fisch ex Hoffm) Benth et Hook F

Bai zhi

152 (2) [1117–1930]

29 (2)

14 (2)

Yesd

Glycyrrhiza spp

Gan cao

143 (3) [682–1949]

16 (5)

13 (3)

No

Xanthium sibiricum Patr

Cang er (zi)

135 (4) [1253–1930]

26 (3)

12 (4)

Yesd

Mentha haplocalyx Briq

Bo he

135 (4) [1253–1949]

16 (5)

6 (8)

No

Ligusticum chuanxiong Hort

Chuan xiong

134 (6) [1117–1924]

12 (7)

6 (8)

No

Scutellaria baicalensis Georgi

Huang qin

102 (7) [1117–1949]

22 (4)

11 (5)

No

Saposhnikovia divaricata (Turcz) Schischk

Fang feng

88 (8) [1117–1911]

7 (18)

3 (21)

No

Panax ginseng C A Mey

Ren shen

69 (9) [1117–1911]

0 (NA)

0 (NA)

No

Allium fistulosum L

Cong (bai)

69 (9) [1117–1930]

0 (NA)

0 (NA)

No

Angelica sinensis (Oliv) Diels

Dang gui

64 (11) [1117–1911]

4 (29)

4 (15)

No

Camellia sinensis (L) Kuntze

Cha (ye)

64 (11) [1253–1928]

0 (NA)

0 (NA)

No

Poria cocos Wolf

Fu ling

62 (13) [1132–1945]

10 (9)

7 (6)

No

Schizonepeta tenuifolia Briq

Jing jie

56 (14) [1117–1911]

8 (15)

1 (42)

No

Ophiopogon japonicus (L f) Ker-Gawl

Mai men dong

52 (15) [1117–1883]

0 (NA)

0 (NA)

No

Platycodon grandiflorum (Jacq) A DC

Jie geng

49 (16) [1358–1949]

11 (8)

5 (12)

No

Gardenia jasminoides Elli

Zhi zi

48 (17) [1358–1949]

9 (12)

2 (28)

No

Pinellia ternata (Thunb) Breit (processed)

Ban xia (fa)

45 (18) [1132–1945]

0 (NA)

1 (42)

No

Asarum spp

Xi xin

44 (19) [1266–1924]

5 (26)

3 (21)

Yesd

Gypsum fibrosum

Shi gao

42 (20) [1117–1934]

5 (26)

0 (NA)

No

Zingiber officinale Ros.; fresh/dried

Jiang; sheng/gan

40; 28/12 (21) [1117–1911]

0 (NA)

0 (NA)

No

Atractylodes macrocephala Koidz

Bai zhu

37 (22) [1358–1911]

3 (33)

6 (8)

No

  1. Abbreviations: RS rhinosinusitis, SR systematic review
  2. aA complete list of the source species for these herbs is available in the Chinese pharmacopoeia [35]. The use of some herbs/ingredients may be restricted in some countries e.g. Asarum spp. Readers are advised to comply with relevant regulations. Herb frequencies include unnamed formulae
  3. bYears are based on when the books were written or published. These may be approximate. See [32] for how book years were determined
  4. cSR 1 is Cui J et al. 2022; SR 2 is Cui J et al. 2023
  5. dFor bi yuan