Fig. 7

The effects of crude methanolic plant extracts on HL60 cell lines. Crude methanolic plant extracts were tested for their antiproliferative effect on HL60 cell line at a concentration of 250 µg/mL. Camptothecin was used as a positive control at a concentration of 10 μg/mL. The negative control contained cells and RPMI media only. The cells were incubated with test solutions and cell viability was determined after 72 h. The values are for the mean ± SD for n = 3. All treatments were compared to cells only to determine the level of significance. The level of significance is denoted as follows: **** P < 0.0001. Plant extracts A. pungu, C. edulis, F. indica, L. ocymifolia, L. martinicensis, P. kalachariensis, S. cocculoides, S. spinosa and V. verrucosum significantly inhibited the proliferation of HL60 cells and V. verrucosum was the most active