Fig. 1

The effect of crude methanolic plant extracts on normal murine peritoneal cells. Crude methanolic plant extracts were tested on normal murine peritoneal cells for their cytotoxic activity at a concentration of 250 µg/mL and chlorambucil was used as a positive control at a concentration of 10 μg/mL. The negative control contained cells and RPMI media only. The cells were incubated with test solutions and cell viability was determined after 72 h. The values are for mean ± SD for n = 3. All treatments were compared to cells only to determine the significant difference. The level of significance was denoted as follows: ****P < 0.0001. Methanolic plant extracts (A. pungu, C. edulis, F. indica, S. cocculoides, S. spinosa and V. verrucosum) significantly reduced cell viability and they were considered cytotoxic