Fig. 6
From: Effect and mechanisms of shikonin on breast cancer cells in vitro and in vivo
Shikonin disrupts the mitochondrial function of 4T1 cells. (A) Representative scatter plots of the mitochondrial membrane potential status in 4T1 cells treated with PBS, 400 ng/mL doxorubicin hydrochloride (DOX), 200 ng/mL shikonin, and 800 ng/mL shikonin for 48 h. (B) Statistical analysis of percentage of cells with low mitochondrial membrane potential. Data are presented as mean ± SEM (n = 3); *P values < 0.05, **P < 0.01