Fig. 5
From: Effect and mechanisms of shikonin on breast cancer cells in vitro and in vivo

Shikonin induces excessive production of ROS by 4T1 cells. (A) Flow cytometry detection of induced production of ROS in the PBS, DOX, LD-SK and HD-SK groups after 24 h. (B) Statistical analysis of ROS level in 4T1 cells after the different treatments. Data are presented as mean ± SEM (n = 3); **P < 0.01